CD34 Antibody

Description

Product Name CD34 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total CD34 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.377~381(Q-H-V-V-A) derived from Human CD34.
Target Name CD34
Alternative Names CD34
Accession No. Swiss-Prot: P28906
NCBI Protein: NP_001020280.1
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 110kd
Western blotting: 1:500~1:1000

Images

Western blot analysis of extract from HUVEC cells and Hematopoietic Stem Cells from Umbilical Cord Blood using CD34 Antibody #AB21469

Background

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Fackler M.J.et.al(1990)Chem. 265:11056-11061

Published Papers

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