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SOX2 AntibodyAB21425

Catalog No.	Package Size	Price
AB21425-1	50ul	$189.00
AB21425-2	100ul	$279.00
AB21425-4	25ul	$119.00

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Description

Product Name SOX2 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total SOX2 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2
Target Name SOX2
Alternative Names Transcription factor SOX-2
Accession No. Swiss-Prot: P48431
NCBI Protein: NP_003097.1
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 35kd
Western blotting: 1:1000

Images

Western blot analysis of extracts from human Umbilical cord mesenchymal stem cell using SOX2 Antibody #AB21425.

Background

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

Yuan H, et al. Genes Dev. 1995 Nov 1;9(21):2635-45
Muta M, et al. Genes Cells 2002 Aug;7(8):791-805
Tomioka M, et al. Nucleic Acids Res. 2002 Jul 15; 30(14): 3202-3213.

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