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ELAC2 AntibodyAB36441

  Catalog No. Package Size Price
AB36441 100ul $279.00

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Description
  • Product Name ELAC2 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications WB IHC
  • Species Reactivity Hu Ms Rt
  • Specificity The antibody detects endogenous levels of total ELAC2 protein.
  • Immunogen Type Recombinant Protein
  • Immunogen Description Fusion protein corresponding to residues near the C terminal of human elaC ribonuclease Z 2
  • Target Name ELAC2
  • Alternative Names ELC2; HPC2; COXPD17
  • Accession No. Swiss-Prot#: Q9BQ52
    NCBI Gene ID: 60528
    Gene Accssion: BC001939
  • SDS-PAGE MW 92kd
  • Concentration 1.5mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Images
  • ELAC2 Antibody - Absci

    Gel: 6%SDS-PAGE
    Lysates (from left to right): LoVo and Hela cell
    Amount of lysate: 40ug per lane
    Primary antibody: 1/250 dilution
    Secondary antibody dilution: 1/8000
    Exposure time: 1 minute

  • ELAC2 Antibody - Absci

    Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #AB36441 at dilution 1/30.

Background

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

    Please let us know if you have published research using #AB36441 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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