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IGFBP-3 AntibodyAB21671

  Catalog No. Package Size Price
AB21671-1 50ul $189.00
AB21671-2 100ul $279.00
AB21671-4 25ul $119.00

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Description
  • Product Name IGFBP-3 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of total IGFBP-3 protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.185~189(R-Y-K-V-D) derived from Human IGFBP-3.
  • Target Name IGFBP-3
  • Alternative Names IBP3; BP-53;
  • Accession No. Swiss-Prot: P17936
    NCBI Protein: NP_001013416.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 24-41kd
Western blotting: 1:500~1:1000
 

Images
  • IGFBP-3 Antibody - Absci

    Western blot analysis of extracts from various cells using IGFBP-3 Antibody #AB21671.

Background

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Roghani M., Segovia B., Whitechurch O., Binoux M.Growth Regul. 1:125-130(1991)
Ikonen M., Liu B., Hashimoto Y., Ma L. Cohen P.Proc. Natl. Acad. Sci. U.S.A. 100:13042-13047(2003)
Zhou W., Ross M.M., Tessitore A. J. Proteome Res. 8:5523-5531(2009)

    Please let us know if you have published research using #AB21671 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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