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CCR5(CD195) AntibodyAB21666

  Catalog No. Package Size Price
AB21666-1 50ul $189.00
AB21666-2 100ul $279.00
AB21666-4 25ul $119.00

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Description
  • Product Name CCR5(CD195) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous level of total CCR5(CD195) protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.11~15(D-I-N-Y-Y) derived from Human CCR5(CD195).
  • Target Name CCR5(CD195)
  • Alternative Names CKR5; CD195; CKR-5
  • Accession No. Swiss-Prot: P51681
    NCBI Protein: NP_000570.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 41kd
Western blotting: 1:500~1:1000

Images
  • CCR5(CD195) Antibody - Absci

    Western blot analysis of extracts from Mouse liver tissue using CCR5(CD195) Antibody #AB21666.

Background
Receptor for a number of inflammatory CC-chemokines including MIP-1-a, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Samson M., Labbe O., Mollereau C. Biochemistry 35:3362-3367(1996)
Raport C.J., Gosling J., Schweichart V.L. J. Biol. Chem. 271:17161-17166(1996)
Combadiere C., Ahuja S.K., Tiffany H.L., Murphy P.M.J. Leukoc. Biol. 60:147-152(1996)
    Please let us know if you have published research using #AB21666 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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