MAP2 Antibody

Description

Product Name MAP2 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB IF
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total MAP2 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.1819~1823 (T-A-A-L-A) derived from Human MAP2.
Target Name MAP2
Alternative Names MAP2A; MAP2B; MAP2C
Accession No. Swiss-Prot: P11137
NCBI Protein: NP_002365.3
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 55-75(2c/2d), 280(2a/2b)kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200

Images

Western blot analysis of extract from C6 cells using MAP2 Antibody #AB21636
Immunofluorescence staining of paraffin-embedded Glioma cells of Spinal Cord using MAP2 Antibody #AB21636.

Background

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

DeGiorgis J.A., Jaffe H., Moreira J.E., Carlotti C.G. Jr. Proteome Res. 4:306-315(2005)
Olsen J.V., Blagoev B., Gnad F., Macek B. Mann M.Cell 127:635-648(2006)
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. Science 316:1160-1166(2007)

Published Papers

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