Predicted MW: 62kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene
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Cavigelli M, et al. (1995) EMBO J. 14:5957-5964.
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