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LPAM-1(Integrin a4, CD49d) AntibodyAB21616

  Catalog No. Package Size Price
AB21616-1 50ul $189.00
AB21616-2 100ul $279.00
AB21616-4 25ul $119.00

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  • Product Name LPAM-1(Integrin a4, CD49d) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of total LPAM-1(Integrin a4, CD49d) protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.1024~1028(Y-I-N-S-K) derived from Human LPAM-1(Integrin a4, CD49d).
  • Target Name LPAM-1(Integrin a4,CD49d)
  • Alternative Names IA4; MGC90518; ITGA4
  • Accession No. Swiss-Prot: P13612
    NCBI Protein: NP_000876.3
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 70 140 180kd
Western blotting: 1:500~1:1000

  • LPAM-1(Integrin a4, CD49d) Antibody - Absci

    Western blot analysis of extract from JK and Raji cells using LPAM-1(Integrin a4, CD49d) Antibody #AB21616

Integrins a-4/beta-1 (VLA-4) and a-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin a-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin a-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Iida J., Meijne A.M.L., Oegema T.R. Jr. J. Biol. Chem. 273:5955-5962(1998)
Liu S., Thomas S.M., Woodside D.G., Rose D.M. Nature 402:676-681(1999)
    Please let us know if you have published research using #AB21616 so that we can cite your reference.
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    Browsing historyclear
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  

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