Keratin 19 Antibody

Description

Product Name Keratin 19 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB IHC
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total Keratin 19 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.392~396(N-N-L-S-A) derived from Human Keratin 19.
Target Name Keratin 19
Alternative Names K19, K1CS, MGC15366, KRT19, CK19
Accession No. Swiss-Prot: P08727
NCBI Protein: NP_002267.2
SDS-PAGE MW 41kd
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 41kd
Western blotting: 1:500~1:1000

Images

Western blot analysis of extract from rat and mouse brain tissue using Keratin 19 Antibody #AB21615
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using Keratin 19 Antibody #AB21615 (left) or the same antibody preincubated with blocking peptide (right).
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using Keratin 19 Antibody #AB21615 (left) or the same antibody preincubated with blocking peptide (right).

Background

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Stone M.R., O'Neill A., Catino D., Bloch R.J.
Mol. Biol. Cell 16:4280-4293(2005)

Published Papers

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