FOXP2 Antibody

Description

Product Name FOXP2 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total FOXP2 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.707~711(E-E-P-L-S) derived from Human FOXP2.
Target Name FOXP2
Alternative Names SPCH1; CAGH44; TNRC10
Accession No. Swiss-Prot: O15409
NCBI Protein: NP_055306.1
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 85kd
Western blotting: 1:500~1:1000

Images

Western blot analysis of extract from JK, Raji and 293 cells using FOXP2 Antibody #AB21608

Background

Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language.

Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004)

Published Papers

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