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Synapsin(phospho-Ser549) AntibodyAB11568

  Catalog No. Package Size Price
AB11568-1 50ul $189.00
AB11568-2 100ul $279.00
AB11568-4 25ul $119.00

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Description
  • Product Name Synapsin(phospho-Ser549) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Applications WB
  • Species Reactivity Hu Rt Ms
  • Specificity The antibody detects endogenous level of Synapsin only when phosphorylated at serine 549.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around phosphorylation site of serine 549(P-A-S(p)-P-S)derived from Rat Synapsin
  • Target Name Synapsin
  • Modification Phospho-Ser549
  • Alternative Names Syn-1; synapsin I;
  • Accession No. Swiss-Prot: O88935
    NCBI Protein: NP_038708.3
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 78kd
Western blotting: 1:500~1:1000

Images
  • Synapsin(phospho-Ser549) Antibody - Absci

    Western blot analysis of extract from rat brain and mouse brain tissue using Synapsin(phospho-Ser549) Antibody using #AB11568

  • Synapsin(phospho-Ser549) Antibody - Absci

    Western blot analysis of extracts from Rat brain tissue or calf intestinal phosphatase (CIP), using Synapsin (phospho-Ser549) Antibody #AB11568.

Background

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level

Greengard, P. (1987) Mol Neurobiol 1, 81-119.
Hosaka, M. et al. (1999) Neuron 24, 377-87.

    Please let us know if you have published research using #AB11568 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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