PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsIHC IF
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous level of total CDK6 protein.
Immunogen TypePeptide-KLH
Immunogen DescriptionPeptide sequence around aa.11~15 (Q-Q-Y-E-C) derived from Human CDK6.
Target NameCDK6
Alternative Names Serine/threonine-protein kinase PLSTIRE
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using CDK6(Ab-13) Antibody #AB21542(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using CDK6(Ab-13) Antibody #AB21542.
Background
Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.