Welcome     Login   Register   Message Board   
Your Position: Home > Cell Signal Transduction > HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody

HDAC4/HDAC5/HDAC9(Ab-246/259/220) AntibodyAB21517

  Catalog No. Package Size Price
AB21517-1 50ul $189.00
AB21517-2 100ul $279.00
AB21517-4 25ul $119.00

Quantity:  Total:   
 

Review:comment rank 5 pdf

Availability: promotionYes

add promotion
Description
  • Product Name HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB IHC IF
  • Species Reactivity Human Mouse
  • Specificity The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9.
  • Target Name HDAC4/HDAC5/HDAC9
  • Alternative Names HD4/HD5/HD9
  • Accession No. Swiss-Prot: P56524 Q9UQL6 Q9UKV0
    NCBI Protein: NP_006028.2 NP_001015053.1 NP_055522.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 140 124 111 kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Images
  • HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody - Absci

    Western blot analysis of extracts from 293 and Hela cells using HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody #AB21517.

  • HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody - Absci

    Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody #AB21517(left) or the same antibody preincubated with blocking peptide(right).

  • HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody - Absci

    Immunofluorescence staining of methanol-fixed Hela cells using HDAC4/HDAC5/HDAC9(Ab-246/259/220) Antibody #AB21517.

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Cress, W.D. and Seto, E. (2000) J Cell Physiol 184, 1-16.
Vigushin, D.M. and Coombes, R.C. (2004) Curr. Cancer Drug Targets 4, 205-218.
Marmorstein, R. (2001) Cell Mol Life Sci 58, 693-703.
Thiagalingam, S. et al. (2003) Ann. N.Y. Acad. Sci. 983, 84-100.

    Please let us know if you have published research using #AB21517 so that we can cite your reference.
Customer Reviews and Rankings
  • No comment
  • Total 0 results, divided into1 pages. First Prev Next Last

    My Review

    Username: Anonymous user
    E-mail:
    Ratings:
    Content:
    Verification code: captcha
     
    Protocol
    Browsing historyclear
    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


    © 2017, AbSci All Rights Reserved. E-mail: info@abscitech.com
    南京川博生物技术有限公司版权所有
    苏B1-20150380 苏ICP备15009006号-1