CD19 Antibody

Description

Product Name CD19 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were purified by affinity purification using immunogen.
Applications WB IHC
Species Reactivity Hu
Specificity The antibody detects endogenous level of total CD19 protein.
Immunogen Type Recombinant Protein
Immunogen Description Recombinant protein of human CD19.
Target Name CD19
Alternative Names B4; CVID3;
Accession No. Swiss-Prot:P15391
NCBI Gene ID:930
SDS-PAGE MW 61KD
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20˚C

Application Details

Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200

Images

Western blot analysis of extracts of various cell lines, using CD19 antibody.
Immunohistochemical analysis of paraffin-embedded human smooth muscle cancer using CD19 antibody at dilution of 1:200 (400x lens).
Immunohistochemical analysis of paraffin-embedded human thyroid cancer using CD19 antibody at dilution of 1:200 (400x lens).
Immunohistochemical analysis of paraffin-embedded human breast cancer using CD19 antibody at dilution of 1:200 (400x lens).

Background

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Published Papers

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