Predicted MW: 180kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76
Kadowaki T, et al. (2000) J Clin Invest; 106(4): 459-465
Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645
Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97(5): 2355-2360
My Review
© 2017, AbSci All Rights Reserved. E-mail: info@abscitech.com
南京川博生物技术有限公司版权所有
苏B1-20150380 苏ICP备15009006号-1