ANXA2 (Phospho-Ser26) Antibody

Description

Product Name ANXA2 (Phospho-Ser26) Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Applications WB
Species Reactivity Hu
Specificity The antibody detects endogenous levels of ANXA2 only when phosphorylated at serine 26.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around phosphorylation site of Serine 26 (Y-G-S(p)-V-K) derived from Human ANXA2.
Target Name ANXA2
Modification Phospho-Ser26
Alternative Names Annexin A2; Annexin II; Annexin-2; CAL1H; Calpactin I heavy chain
Accession No. Swiss-Prot#: P07355;
NCBI Gene#: 302;
NCBI Protein#: NP_001002857.1.
SDS-PAGE MW 38kd
Concentration 1.0mg/ml
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20˚C/1 year

Application Details

Western blotting: 1:500~1:1000

Images

Western blot analysis of extracts from HepG2 cells JK cells and K562 cells using ANXA2 (Phospho-Ser26) Antibody #AB11839.The lane on the right is treated with the antigen-specific peptide.

Background

Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.

Huang K.-S., Cell 46:191-199(1986).
Spano F., Gene 95:243-251(1990).
Bechtel S., BMC Genomics 8:399-399(2007).

Published Papers

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