Immunohistochemistry: 1:50~1:100
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Cao Z., Science 271:1128-1131(1996).
Reichwald K., Mamm. Genome 11:182-190(2000).
Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).
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