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CD45 (Phospho-Ser1007) AntibodyAB11993

  Catalog No. Package Size Price
AB11993-1 50ul $189.00
AB11993-2 100ul $279.00

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Description
  • Product Name CD45 (Phospho-Ser1007) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Applications WB
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of CD45 only when phosphorylated at serine 1007.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around phosphorylation site of serine 1007 (D-D-S(p)-D-S) derived from Human CD45.
  • Target Name CD45
  • Modification Phospho-Ser1007
  • Alternative Names L-CA; LY-5; Leukocyte common antigen precursor; PTPRC; T200
  • Accession No. Swiss-Prot#: P08575;
    NCBI Gene#: 5788;
    NCBI Protein#: NP_001254727.1
  • SDS-PAGE MW 150kd
  • Concentration 1.0mg/ml
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C/1 year
Application Details

Western blotting: 1:500~1:1000

Images
  • CD45 (Phospho-Ser1007) Antibody - Absci

    Western blot analysis of extracts from HeLa cells treated with TNF using Phospho-CD45 (Ser1007) antibody #AB11993.The lane on the right is treated with the antigen-specific peptide.

Background

Protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; protein kinase binding.

Wang Y, Guo W, Liang L, Esselman WJ (1999)J Biol Chem 274, 7454-61.

    Please let us know if you have published research using #AB11993 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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