SpecificityThe antibody detects endogenous level of total MMP-9 protein.
Immunogen TypePeptide-KLH
Immunogen DescriptionPeptide sequence around aa.110-114(F-E-G-D-L) derived from Human MMP-9.
Target NameMMP-9
Alternative NamesGELB, CLG4B, MMP-9, MANDP2,
Concentration1.0mg/ml
Application Details
Predicted MW: 84 92kd Western blotting: 1: 500~1: 1000
Images
Western blot analysis of extracts from Hela cells using MMP-9 Antibody #AB21677.
Background
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.