StorageStore at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Application Details
Vol.per.Test: 10 μl/Test
Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.
Images
Mouse spleen cells analyzed with PE mouse CD4 mAb.
Background
The 4AM15 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor. It is a member of the lg superfamily,primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC classII and associating with the protein tyrosine kinase, lck.
1. Nakamura.T. 1992.Personal communication.
2. Bendelac.A.1995.Mouse NK1 T Cells.Curr.Opin.Immunol.7:367-374
3. Shevach,E.M.2000.Regulatory T cells in autoimmunity.Annu.Rev.Immunol.
Yes
