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Mouse anti-Human CD62L, PE Conjugated mAbAB28189

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Description

Product Name Mouse anti-Human CD62L, PE Conjugated mAb
Host Species Mouse
Clonality Monoclonal
Clone No. 4AE56
Isotype IgG1
Applications FC
Species Reactivity Hu
Conjugates PE
Target Name CD62L
Formulation Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Storage Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.

Application Details

Vol.per.Test: 10 μl/Test

Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

Images

Human peripheral blood lymphocytes analyzed with PE CD62L mAb

Background

4AE56 reacts with L-selectin, an 80 kDa leukocyte-endothelial cell adhesion molecule 1 (LECAM-1). CD62L is expressed on most peripheral blood B cells, T cells, some NK cells, monocytes and granulocytes. CD62L mediates lymphocyte homing to high endothelial venules of peripheral lymphoid tissue and leukocyte rolling on activated endothelium at inflammatory sites.

1. Bevilacqua, M et al ( 1991) : Cell 67:233.

2. Polley, MJ et al ( 1991) , Proc. Natl. Acad. Sci. USA 88:6224.

3. Smith, CW et al ( 1991) J Clin. Invest . 87:609.

4. Picker, LJ et al ( 1991) Cell 66:921.

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