Welcome     Login   Register   Message Board   
Your Position: Home > Neuroscience Research > Tau(Ab-205) Antibody

Tau(Ab-205) AntibodyAB21097

  Catalog No. Package Size Price
AB21097-1 50ul $189.00
AB21097-2 100ul $279.00
AB21097-4 25ul $119.00

Quantity:  Total:   
 

Review:comment rank 5 pdf

Availability: promotionYes

add promotion
Description
  • Product Name Tau(Ab-205) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous level of total Tau protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.203~207 (P-G-T-P-G) derived from Human Tau.
  • Target Name Tau
  • Alternative Names Neurofibrillary tangle protein; Paired helical filament-tau; MAPT; MTAPT; MTBT1
  • Accession No. Swiss-Prot: P10636
    NCBI Protein: NP _001116538.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 48 62 78 kd
Western blotting: 1:500~1:1000

Images
  • Tau(Ab-205) Antibody - Absci

    Western blot analysis of extracts from Mouse Brain tissue using Tau(Ab-205) Antibody #AB21097.

Background

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

del C Alonso A, et al. (2004) J Biol Chem; 279(33): 34873-81
Li G, Yin H, Kuret J (2004) J Biol Chem; 279(16): 15938-45
Giasson BI, et al. (2002) Biochemistry; 41(51): 15376-87
Liu F, et al. (2002) FEBS Lett; 530(1-3): 209
Taniguchi T, et al. (2001) J Biol Chem; 276(13): 10025-31

    Please let us know if you have published research using #AB21097 so that we can cite your reference.
Customer Reviews and Rankings
  • No comment
  • Total 0 results, divided into1 pages. First Prev Next Last

    My Review

    Username: Anonymous user
    E-mail:
    Ratings:
    Content:
    Verification code: captcha
     
    Protocol
    Browsing historyclear
    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


    © 2017, AbSci All Rights Reserved. E-mail: info@abscitech.com