Predicted MW: 81kd
Western blotting: 1:500~1:1000
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-90.
Wang Q, et al. (2003) J Biol Chem 278(48): 47731-43.
Gautreau A, et al. (1999) Proc Natl Acad Sci U S A: 96(13): 7300-5.
Crepaldi T, et al. (1997) J Cell Biol: 28; 138(2): 423-34.
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