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Ezrin(Ab-353) AntibodyAB21094

  Catalog No. Package Size Price
AB21094-1 50ul $189.00
AB21094-2 100ul $279.00
AB21094-4 25ul $119.00

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Description
  • Product Name Ezrin(Ab-353) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of total Ezrin protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.351~355 (Q-D-Y-E-E) derived from Human EZRIN.
  • Target Name Ezrin
  • Alternative Names Cytovillin; EZRI; VIL2; Villin 2; p81
  • Accession No. Swiss-Prot: P15311
    NCBI Protein: NP_001104547.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 81kd
Western blotting: 1:500~1:1000

Images
  • Ezrin(Ab-353) Antibody - Absci

    Western blot analysis of extracts from MDA and SKOV3 cells using Ezrin(Ab-353) Antibody #AB21094.

Background

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-90.
Wang Q, et al. (2003) J Biol Chem 278(48): 47731-43.
Gautreau A, et al. (1999) Proc Natl Acad Sci U S A: 96(13): 7300-5.
Crepaldi T, et al. (1997) J Cell Biol: 28; 138(2): 423-34.

    Please let us know if you have published research using #AB21094 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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