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VEGFR2(Ab-1214) AntibodyAB21078

  Catalog No. Package Size Price
AB21078-1 50ul $189.00
AB21078-2 100ul $279.00
AB21078-4 25ul $119.00

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Description
  • Product Name VEGFR2(Ab-1214) Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Applications WB IHC IF
  • Species Reactivity Hu Ms Rt
  • Specificity The antibody detects endogenous level of total VEGFR2 protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.1212~1216 (F-H-Y-D-N) derived from Human VEGFR2.
  • Target Name VEGFR2
  • Alternative Names FLK1; KDR; VGFR2; VGR2; kinase insert domain receptor
  • Accession No. Swiss-Prot: P35968
    NCBI Protein: NP_002244.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details

Predicted MW: 230kd
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Images
  • VEGFR2(Ab-1214) Antibody - Absci

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2(Ab-1214) Antibody #AB21078(left) or the same antibody preincubated with blocking peptide(right).

  • VEGFR2(Ab-1214) Antibody - Absci

    Immunofluorescence staining of methanol-fixed MCF cells using VEGFR2(Ab-1214) Antibody #AB21078.

Background

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Lamalice L, et al. (2004). Oncogene.23(2): 434-445.
Takahashi T, et al. (2001). EMBO J .20(11): 2768-2778.

    Please let us know if you have published research using #AB21078 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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