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GATA1(Ab-310) AntibodyAB21042

Catalog No.	Package Size	Price
AB21042-1	50ul	$189.00
AB21042-2	100ul	$279.00
AB21042-4	25ul	$119.00

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Description

Product Name GATA1(Ab-310) Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total GATA1 protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.308~312 (K-A-S-G-K) derived from Human GATA1.
Target Name GATA1
Alternative Names GAT1; GATA1; GF-1; NF-E1;
Accession No. Swiss-Prot: P15976
NCBI Protein: NP_002040.1
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 43kd
Western blotting: 1:500~1:1000

Images

Western blot analysis of extracts from K562 and HT29 cells using GATA1(Ab-310) Antibody #AB21042.

Background

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Kadri Z, et al.(2005)Mol Cell Biol 2005 Sep; 25(17): 7412-22.

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