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PEG10 Monoclonal AntibodyAB27129
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Description
Product NamePEG10 Monoclonal Antibody
Host SpeciesMouse
ClonalityMonoclonal
Clone No.1E12-F12-C12
IsotypeIgG1
PurificationAffinity purified
ApplicationsE WB IP
Species ReactivityHu Ms Rb P
Immunogen TypeRecombinant protein
Immunogen DescriptionPurified recombinant human PEG10 protein fragments expressed in E.coli.
Target NamePEG10
Alternative NamesEDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Application Details
Predicted MW: 55kd Western blotting: 1:1000
Images
Western blot detection of PEG10 in Hela cell lysates using PEG10 antibody (1:1000 diluted). Predicted band size:55KDa. Observed band size:55KDa
Immunoprecipitation analysis of Hela cell lysates using PEG10 antibody
Background
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.
Yes
