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PI 3-kinase p85β (phospho Tyr464) Polyclonal AntibodyAB13621

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Description

Product Name PI 3-kinase p85β (phospho Tyr464) Polyclonal Antibody
Host Species Rabbit
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Applications WB,ELISA
Species Reactivity Human,Mouse,Rat
Specificity Phospho-PI 3-kinase p85β (Y464) Polyclonal Antibody detects endogenous levels of PI 3-kinase p85β protein only when phosphorylated at Y464.
Immunogen Description Synthesized phospho-peptide around the phosphorylation site of human PI 3-kinase p85β (phospho Tyr464)
Alternative Names PIK3R2; Phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta;
Accession No. Swiss Prot:O00459
GeneID:5296
SDS-PAGE MW 85kd
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -20˚C/1

Application Details

Western Blot: 1/500 - 1/2000.
ELISA: 1/10000. Not yet tested in other applications.

Background

phosphoinositide-3-kinase regulatory subunit 2(PIK3R2) Homo sapiens Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2012],

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