DPP3 Polyclonal Antibody

Description

Product Name DPP3 Polyclonal Antibody
Host Species Rabbit
Clonality Polyclonal
Isotype IgG
Purification Affinity purification
Applications WB,IHC
Species Reactivity Human,Mouse,Rat
Immunogen Description Recombinant fusion protein of human DPP3 (NP_569710.2).
Alternative Names DPP3; DPPIII; dipeptidyl peptidase 3
Accession No. Swiss-Prot#:Q9NY33
NCBI Gene ID:10072
Calculated MW 83kDa
Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
Storage Store at -20˚C

Application Details

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Images

Western blot analysis of extracts of various cell lines, using DPP3 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human gastric cancer using DPP3 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using DPP3 at dilution of 1:100 (40x lens).

Background

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.

Published Papers

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