Welcome     Login   Register   Message Board   
Your Position: Home > Phospho-specific Antibody > ULK1(Phospho-Ser757) Antibody

ULK1(Phospho-Ser757) Antibody12871

  Catalog No. Package Size Price
12871-1 50ul $189.00
12871-2 100ul $279.00

Quantity:  Total:   

Review:comment rank 5 pdf

Availability: promotionYes

add promotion
  • Product Name ULK1(Phospho-Ser757) Antibody
  • Brief Description Rabbit Polyclonal
  • Host Species Rabbit
  • Clonality Polyclonal
  • Applications WB
  • Species Reactivity Hu Ms Rt
  • Specificity Phospho-ULK1(S757) Antibody detects endogenous levels of ULK1 only when phosphorylated at S757
  • Immunogen Type Peptide-KLH
  • Immunogen Description A synthesized peptide derived from human ULK1(Phospho-Ser757)
  • Alternative Names ATG 1 antibody ATG1 antibody ATG1 autophagy related 1 homolog antibody ATG1A antibody Autophagy related protein 1 homolog antibody Autophagy-related protein 1 homolog antibody FLJ38455 antibody FLJ46475 antibody hATG1 antibody KIAA0722 antibody Serine threonine protein kinase ULK1 antibody Serine threonine protein kinase Unc51.1 antibody Serine threonine-protein kinase ULK1 antibody ULK 1 antibody ULK1 antibody ULK1_HUMAN antibody Unc 51 (C. elegans) like kinase 1 antibody UNC 51 antibody Unc 51 like kinase 1 antibody Unc-51 like kinase 1 (C. elegans) antibody Unc-51-like kinase 1 antibody UNC51 antibody UNC51 C. elegans homolog of antibody Unc51.1 antibody
  • Accession No. Swiss-Prot#:O75385
    NCBI Gene ID8408
  • Calculated MW 140-150
  • Concentration 1.0mg mL
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

WB dilution:1:1000

  • ULK1(Phospho-Ser757) Antibody - Absci

    Western blot analysis ULK1(Phospho-Ser757) using A431 whole cell lysates

Product Description
Two related serine,threonine kinases, UNC-51-like kinase -1 and -2 (ULK1, ULK2), were discovered as mammalian homologs of the C. elegans gene UNC-51 in which mutants exhibited abnormal axonal extension and growth (1-4). Both proteins are widely expressed and contain an amino-terminal kinase domain followed by a central proline,serine rich domain and a highly conserved carboxy-terminal domain. The roles of ULK1 and ULK2 in axon growth have been linked to studies showing that the kinases are localized to neuronal growth cones and are involved in endocytosis of critical growth factors such as NGF (5). Yeast two-hybrid studies found ULK1,2 associated with modulators of the endocytic pathway, SynGap, and syntenin (6). Structural similarity of ULK1,2 has also been recognized with the yeast autophagy protein Atg1,Apg1 (7). Knockdown experiments using siRNA demonstrated that ULK1 is essential for autophagy (8), a catabolic process for the degradation of bulk cytoplasmic contents (9,10). It appears that Atg1,ULK1 can act as a convergence point for multiple signals that control autophagy (11), and can bind to several autophagy-related (Atg) proteins, regulating phosphorylation states and protein trafficking (12-16).
    Please let us know if you have published research using #12871 so that we can cite your reference.
Customer Reviews and Rankings
  • No comment
  • Total 0 results, divided into1 pages. First Prev Next Last

    My Review

    Username: Anonymous user
    Verification code: captcha
    Browsing historyclear
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  

    © 2017, AbSci All Rights Reserved. E-mail: info@abscitech.com
    苏B1-20150380 苏ICP备15009006号-1