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Ezh2 (Phospho-Thr367) Antibody12868

  Catalog No. Package Size Price
12868-1 50ul $189.00
12868-2 100ul $279.00

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  • Product Name Ezh2 (Phospho-Thr367) Antibody
  • Brief Description Rabbit Polyclonal
  • Host Species Rabbit
  • Clonality Polyclonal
  • Applications WB
  • Species Reactivity Hu Ms Rt
  • Specificity Phospho-Ezh2 (T367) Antibody detects endogenous levels of Ezh2 only when phosphorylated at T367
  • Immunogen Type Peptide-KLH
  • Immunogen Description A synthesized peptide derived from human Ezh2 (Phospho-Thr367)
  • Alternative Names Enhancer of zeste 2 antibody enhancer of zeste 2 polycomb repressive complex 2 subunit antibody Enhancer of zeste homolog 2 (Drosophila) antibody Enhancer of zeste homolog 2 antibody Enhancer of zeste Drosophila homolog 2 antibody ENX 1 antibody Enx 1h antibody ENX-1 antibody ENX1 antibody Enx1h antibody EZH 2 antibody EZH1 antibody EZH2 antibody EZH2_HUMAN antibody EZH2b antibody Histone-lysine N-methyltransferase EZH2 antibody KMT 6 antibody KMT6 antibody KMT6A antibody Lysine N-methyltransferase 6 antibody MGC9169 antibody WVS antibody WVS2 antibody
  • Accession No. Swiss-Prot#:Q15910
    NCBI Gene ID2146
  • Calculated MW 98
  • Concentration 1.0mg mL
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

WB dilution:1:1000

  • Ezh2 (Phospho-Thr367) Antibody - Absci

    Western blot analysis Ezh2 (Phospho-Thr367) using PMA treated HeLa whole cell lysates

Product Description
The polycomb group (PcG) proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis (1,2). Enhancer of zeste homolog 2 (Ezh2), a member of this large protein family, contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain (3). The SET domain has been linked with histone methyltransferase (HMTase) activity. Moreover, mammalian Ezh2 is a member of a histone deacetylase complex that functions in gene silencing, acting at the level of chromatin structure (4). Ezh2 complexes methylate histone H3 at Lys9 and 27 in vitro, which is thought to be involved in targeting transcriptional regulators to specific loci (5). Ezh2 is deregulated in various tumor types, and its role, both as a primary effector and as a mediator of tumorigenesis, has become a subject of increased interest (6).
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    Browsing historyclear
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  

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