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MEF2C (Phospho-Ser222) Antibody12855

  Catalog No. Package Size Price
12855-1 50ul $189.00
12855-2 100ul $279.00

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  • Product Name MEF2C (Phospho-Ser222) Antibody
  • Brief Description Rabbit Polyclonal
  • Host Species Rabbit
  • Clonality Polyclonal
  • Applications WB
  • Species Reactivity Hu Ms Rt
  • Specificity Phospho-MEF2C (S222) Antibody detects endogenous levels of MEF2C only when phosphorylated at S222
  • Immunogen Type Peptide-KLH
  • Immunogen Description A synthesized peptide derived from human MEF2C (Phospho-Ser222)
  • Alternative Names C5DELq14.3 antibody DEL5q14.3 antibody MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C) antibody MADS box transcription enhancer factor 2 polypeptide C antibody MEF2C antibody MEF2C_HUMAN antibody Myocyte enhancer factor 2C antibody Myocyte specific enhancer factor 2C antibody Myocyte-specific enhancer factor 2C antibody OTTHUMP00000222409 antibody Similar to MADS box transcription enhancer factor 2 polypeptide C antibody
  • Accession No. Swiss-Prot#:Q06413
    NCBI Gene ID4208
  • Calculated MW 51
  • Concentration 1.0mg mL
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

WB dilution:1:1000

  • MEF2C (Phospho-Ser222) Antibody - Absci

    Western blot analysis MEF2C (Phospho-Ser222) using 293 whole cell lysates

Product Description
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
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    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  

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