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Recombinant Human KeRatin, type I cytoskeletal 18(KRT18),partialAP73708

  Catalog No. Package Size Price
AP73708-1 10ug $105.00
AP73708-2 50ug $260.00
AP73708-3 100ug $454.00
AP73708-4 200ug $735.00
AP73708-5 500ug $1240.00
AP73708-6 1mg $1980.00

Quantity:  Total:   
 

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Description
  • Product Name Recombinant Human KeRatin, type I cytoskeletal 18(KRT18),partial
  • Brief Description Recombinant Protein
  • Host Species E.coli
  • Target Name KRT18
  • Alternative Names Cell proliferation-inducing gene 46 protein;Cytokeratin-18; CK-18Keratin-18; K18
  • Accession No. Uniprot ID: P05783
  • Target Species Hu
  • SDS-PAGE MW 31.106kDa
  • Target Length Partial,102-396aa
  • Tag Info N-terminal 6xHis-tagged
  • Target Sequence ETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDAL
  • Formulation Tris-based buffer,50% glycerol
  • Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20˚C/-80˚C. The shelf life of lyophilized form is 12 months at -20˚C/-80˚C.
Application Details

Greater than 90% as determined by SDS-PAGE.

Background
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma mbrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection
Regerences
Comparison of mouse and human keratin 18 a component of intermediate filaments expressed prior to implantation.Oshima R.G., Millan J.L., Cecena G.Differentiation 33:61-68(1986)
    Please let us know if you have published research using #AP73708 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  


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