PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
ApplicationsWB
Species ReactivityHu
SpecificityBRCA1 (Phospho-Ser1497) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1497
Immunogen TypePeptide
Immunogen DescriptionA synthesized peptide derived from human BRCA1 (Phospho-Ser1497)
Target NameBRCA1
ModificationPhospho-Ser1497
Alternative NamesBRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS