IL6 Monoclonal Antibody

Description

Product Name IL6 Monoclonal Antibody
Host Species Mouse
Clonality Monoclonal
Purification protein G purifed
Applications IHC
Species Reactivity Hu
Specificity specific for human Interleukin-6 denatured and native forms
Immunogen Type protein
Immunogen Description Recombinant Human Interleukin-6
Target Name IL6
Alternative Names B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2
Accession No. Swiss-Prot#: P05231
Calculated MW
Concentration 1.0mg/mL
Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage Store at -20˚C

Application Details

Immunohistochemistry: 1:20 - 1:200

Images

Immunohistochemical analysis of paraffin-embedded human prostate tissue using #AB42035 at dilution of 1:200.

Background

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Regerences

[1] "Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin."Hirano T., Yasukawa K., Harada H., Taga T., Watanabe Y., Matsuda T., Kashiwamura S., Nakajima K., Koyama K., Iwamatsu A., Tsunas

Published Papers

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