BNP antibody

Description

Product Name BNP antibody
Host Species Rabbit
Clonality Polyclonal
Purification Purified by antigen-affinity chromatography.
Applications WB
Species Reactivity Hu
Immunogen Type Recombinant Protein
Immunogen Description Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 120 of Human NPPB
Target Name BNP
Accession No. NCBI Gene ID: 4879
NCBI mRNA#: NM_002521
NCBI Protein#: NP_002512
Formulation Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

Application Details

Predicted MW: 15kd
Western blotting: 1:500-1:3000

Images

Sample (30 ug of whole cell lysate)
A: Hela
B: Hep G2
15% SDS PAGE
Primary antibody diluted at 1: 1000

Background

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq]

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