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RAD52 antibodyAB38568

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Description

Product Name RAD52 antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were purified by affinity purification using immunogen.
Applications IHC
Species Reactivity Hu
Specificity The antibody detects endogenous level of total RAD52 antibody.
Immunogen Type Peptide
Immunogen Description A synthetic peptide of human RAD52.
Target Name RAD52
Alternative Names RAD52 homolog (S. cerevisiae)
Accession No. Swiss-Prot#: P43351
NCBI Gene ID: 5893
SDS-PAGE MW 46kd
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20˚C

Application Details

Western blotting: 1:500 - 1:1000
Immunohistochemistry:1:25-1:100

Background

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.

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