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Histone H3(Di-Methyl-Lys4) Rabbit Polyclonal AntibodyABHW068

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Description

Product Name Histone H3(Di-Methyl-Lys4) Rabbit Polyclonal Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Affinity purification using immunogen.
Applications WB
Species Reactivity Hu Rt Ms
Specificity The Histone H3(Di-methyl-Lys4) Rabbit Polyclonal Antibody detects endogenous Histone H3 (Di-methyl-Lys4) protein.
Immunogen Type peptide
Immunogen Description A synthetic Di-methylated peptide corresponding to residues surrounding Lys4 of human histone H3.
Target Name Histone H3(Di-Methyl-Lys4)
Modification Di-Methyl-Lys4
Alternative Names H3 histone antibody; HIST1H3A antibody; Histone cluster 1; H3a antibody
Accession No. Swiss-Prot#:P68431
SDS-PAGE MW 17kd
Concentration 1.0mg/ml
Formulation Purified Rabbit IgG, 1mg/ml in PBS pH7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage Store at -20˚C

Application Details

Western blotting: 1:1000~1:2000

Images

Western blot analysis of 1) Hela, 2)3T3 , 3) Raw264.7, using #ABHW068 diluted at 1:2,000.

Background

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

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