CD93 Antibody

Description

Product Name CD93 Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antigen affinity purification.
Applications WB IHC
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous levels of total CD93 protein.
Immunogen Type Peptide
Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human CD93 molecule
Target Name CD93
Alternative Names C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1
Accession No. Swiss-Prot#: Q9NPY3
NCBI Gene ID: 22918
Gene Accssion: NP_036204
Calculated MW 120kd
Concentration 1.0mg/ml
Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage Store at -20˚C

Application Details

Western blotting: 1:1000-1:3000

Immunohistochemistry: 1:25-1:200

Images

Western blot analysis CD93 using HeLa whole cell lysates
Immunohistochemical analysis of paraffin-embedded Human Colo cancer tissue using #AB37276 at dilution 1/25.
Immunohistochemical analysis of paraffin-embedded Human spleen cancer tissue using #AB37276 at dilution 1/200.

Background

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.

Published Papers

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