PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous level of total FOXP1 protein.
Immunogen TypePeptide-KLH
Immunogen DescriptionPeptide sequence around aa. 669~673 (D-E-P-V-N
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 82~90kd
Western blotting: 1:500~1:1000
Images
Western blot analysis of extract from JK, Raji, Hela and 293 cells using FOXP1 Antibody #AB21637
Background
Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development
Hamdan F.F., Daoud H., Rochefort D., Piton A. J. Hum. Genet. 87:671-678(2010)