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Neuroserpin AntibodyAB21618

Catalog No.	Package Size	Price
AB21618-1	50ul	$189.00
AB21618-2	100ul	$279.00
AB21618-4	25ul	$119.00

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Description

Product Name Neuroserpin Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications WB
Species Reactivity Hu Ms Rt
Specificity The antibody detects endogenous level of total Neuroserpin protein.
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around aa.402~406(T-S-G-H-D) derived from Human Neuroserpin.
Target Name Neuroserpin
Alternative Names PI12; SERPINI1;
Accession No. Swiss-Prot: Q99574
NCBI Protein: NP_001116224.1
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 55kd
Western blotting: 1:500~1:1000

Images

Western blot analysis of extract from Mouse brain tissue using Neuroserpin Antibody #AB21618

Background

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

Davis R.L., Shrimpton A.E., Holohan P.D. Nature 401:376-379(1999)

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