SpecificityPhospho-PINK1 ( T313) Antibody detects endogenous levels of PINK1 only when phosphorylated at T313
Immunogen TypePeptide-KLH
Immunogen DescriptionA synthesized peptide derived from human PINK1 (Phospho- Thr313)
Alternative NamesBRPK antibody
FLJ27236 antibody
mitochondrial antibody
PARK 6 antibody
PARK6 antibody
Phosphatase and Tensin Homolog antibody
PINK 1 antibody
PINK1 antibody
PINK1_HUMAN antibody
Protein kinase BRPK antibody
PTEN induced putative kinase 1 antibody
PTEN induced putative kinase protein 1 antibody
PTEN-induced putative kinase protein 1 antibody
Serine threonine kinase PINK1 mitochondrial antibody
Serine threonine protein kinase PINK1 mitochondrial antibody
Serine threonine-protein kinase PINK1 antibody
Accession No.Swiss-Prot#:Q9BXM7 NCBI Gene ID65018
Calculated MW60 50
Concentration1.0mg mL
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB dilution:1:1000
Images
Western blot analysis PINK1 (Phospho- Thr313) using EGF treated SK-OV3 whole cell lysates
Product Description
PTEN induced putative kinase 1, PINK1, is a mitochondrial serine,threonine kinase involved in the normal function and integrity of mitochondria, as well as in reduction of cytochrome c release from mitochondria (1-3). PINK1 phosphorylates Parkin and promotes its translocation to mitochondria (2). Research studies have shown that mutations in PINK1 are linked to autosomal recessive early onset Parkinson��s disease, and are associated with loss of protective function, mitochondrial dysfunction, aggregation of α-synuclein, as well as proteasome dysfunction (1,3)
Yes
