Predicted MW: 40kd
Western blotting: 1:500~1:1000
MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
Emmanuel G, et al. J. Biol. Chem., Jun 2000; 275: 18767 - 18776
Tintignac LA, et al. Mol Cell Biol. 2004 Feb; 24(4): 1809-1821.
Kitzmann M, et a. Mol Cell Biol. 1999 Apr; 19(4): 3167-3176.
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